Publications

Selected publications from our research group.

Tay JK, Zhu C, Shin JH, Zhu SX, Varma S, Foley JW, Vennam S, Yip YL, Goh CK, Wang Y, Loh KS, Tsao SW, Le QT, Sunwoo JB, West RB. The microdissected gene expression landscape of nasopharyngeal cancer reveals vulnerabilities in FGF and noncanonical NF-κB signaling. Sci Adv. 2022 Apr 8;8(14):eabh2445.
doi: 10.1126/sciadv.abh2445. Epub 2022 Apr 8. PMID: 35394843.

Tay JK, Chan SH, Lim CM, Siow CH, Goh HL, Loh KS. The Role of Epstein-Barr Virus DNA Load and Serology as Screening Tools for Nasopharyngeal Carcinoma. Otolaryngol Head Neck Surg. 2016 Aug;155(2):274-80.
doi: 10.1177/0194599816641038. Epub 2016 May 3. PMID: 27143706.

Tay JK, Khoo ML, Loh WS. Surgical Considerations for Tracheostomy During the COVID-19 Pandemic: Lessons Learned From the Severe Acute Respiratory Syndrome Outbreak. JAMA Otolaryngol Head Neck Surg. 2020 Jun 1;146(6):517-518.
doi: 10.1001/jamaoto.2020.0764. PMID: 32232426.

Tay JK, Lim WS, Loh WS, Loh KS. Sustaining Otolaryngology Services for the Long Haul during the COVID-19 Pandemic: Experience from a Tertiary Health System. Otolaryngol Head Neck Surg. 2020 Jul;163(1):47-50.
doi: 10.1177/0194599820922983. Epub 2020 May 5. PMID: 32366174.

Tay JK, Siow CH, Goh HL, Lim CM, Hsu PP, Chan SH, Loh KS. A comparison of EBV serology and serum cell-free DNA as screening tools for nasopharyngeal cancer: Results of the Singapore NPC screening cohort. Int J Cancer. 2020 May 15;146(10):2923-2931.
doi: 10.1002/ijc.32774. Epub 2020 Jan 8. PMID: 31705522.

Moreno-Nieves UY, Tay JK, Saumyaa S, Horowitz NB, Shin JH, Mohammad IA, Luca B, Mundy DC, Gulati GS, Bedi N, Chang S, Chen C, Kaplan MJ, Rosenthal EL, Holsinger FC, Divi V, Baik FM, Sirjani DB, Gentles AJ, Newman AM, Freud AG, Sunwoo JB. Landscape of innate lymphoid cells in human head and neck cancer reveals divergent NK cell states in the tumor microenvironment. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2101169118.
doi: 10.1073/pnas.2101169118. PMID: 34244432; PMCID: PMC8285950.

Tay JK, Cross GB, Toh ST, Lee CK, Loh J, Lim ZY, Ngiam N, Chee J, Gan SW, Saraf A, Chow WTE, Goh HL, Siow CH, Lian DWQ, Loh WS, Loh KS, Lim CM, Chua YY, Tan TT, Tan HK, Yan B, Ko K, Chan KS, Oon L, Chow VTK, Wang Y, Fuh JYH, Yen CC, Wong JEL, Allen DM. Design and Multicenter Clinical Validation of a 3-Dimensionally Printed Nasopharyngeal Swab for SARS-CoV-2 Testing. JAMA Otolaryngol Head Neck Surg. 2021 May 1;147(5):418-425.
doi: 10.1001/jamaoto.2020.5680. PMID: 33599684; PMCID: PMC7893548.

Tay JK, Cross GB, Sun L, Chia A, Chee J, Loh J, Lim ZY, Ngiam N, Khang WP, Yeap S, Goh HL, Siow CH, Loh WS, Loh KS, Lee CK, Yan B, Chow VTK, Wang Y, Boey F, Wong JEL, Allen DM. Clinical Diagnostic Study of a Novel Injection Molded Swab for SARS-Cov-2 Testing. Infect Dis Ther. 2021 Jun;10(2):1015-1022.
doi: 10.1007/s40121-020-00391-6. Epub 2021 Jan 11. PMID: 33432534; PMCID: PMC7799401.

Wu X, Tay JK, Goh CK, Chan C, Lee YH, Springs SL, Wang DY, Loh KS, Lu TK, Yu H. Digital CRISPR-based method for the rapid detection and absolute quantification of nucleic acids. Biomaterials. 2021 Jul;274:120876.
doi: 10.1016/j.biomaterials.2021.120876. Epub 2021 May 11. PMID: 34034027.